Nonlinear cable equations for axons. II. Computations and experiments with external current electrodes
نویسندگان
چکیده
We have investigated the steady-state potential and current distributions resulting from current injection into a close-fitting channel into which a squid axon is placed. Hybrid computer solutions of the cable equations, using the Hodgkin-Huxley equations to give the membrane current density, were in good agreement with experimental observations. A much better fit was obtained when the Hodgkin-Huxley leakage conductance was reduced fivefold.
منابع مشابه
Nonlinear cable equations for axons. I. Computations and experiments with internal current injection
Steady-state potential and current distributions resulting from internal injection of current in the squid giant axon have been measured experimentally and also computed from nonlinear membrane cable equation models by numerical methods, using the Hodgkin-Huxley equations to give the membrane current density. The solutions obtained by this method satisfactorily reproduce experimental measuremen...
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عنوان ژورنال:
- The Journal of General Physiology
دوره 73 شماره
صفحات -
تاریخ انتشار 1979